Key Points
- Statewide SEP-1 Sepsis Bundle compliance has increased over time. Sepsis mortality declined overall but spiked during the COVID-19 pandemic, indicating challenges in sustaining improvements.
- Higher hospital SEP-1 Sepsis Bundle compliance is associated with lower mortality rates, but the correlation weakened over time (from r = -.31 in 2017 to r = -.17 in 2022) and varied significantly by hospital characteristics such as ownership type and transfer volume.
- Investor-owned hospitals and those with smaller sample sizes exhibited weaker or negligible relationships between compliance and mortality, highlighting the role of contextual factors and the need for hospital-specific strategies.
Read the full article about the association between SEP-1 Sepsis Bundle compliance and SEP-3 in-hospital sepsis mortality rates from 2017 to 2022 in California hospitals: here.