Hospital Quality Transparency Dashboard

Quality Transparency Dashboard Sepsis Mortality Calculation (Update Sept 2023)

How does HQI calculate sepsis mortality?  (ICD-10-CM)


In-hospital mortality rate among acute care discharges meeting the modified Dombrovskiy Method proxy case definition for sepsis. While sepsis and septic shock are proxy-diagnosed per the Third International Consensus Definitions for Sepsis and Septic Shock (SEP-3) based on the presence at discharge of a combination of ICD-10-CM codes, it is not strictly the identified cause of death.


The mortality rate calculation via the modified Dombrovskiy Method for sepsis case identification follows this process:

  1. Identify all inpatient discharges with a diagnosis code (in any position) for septicemia or sepsis
  2. Identify all inpatient discharges with a diagnosis code (in any position) for organ dysfunction
  3. Categorize inpatient discharges with a code in both #1 and #2 as sepsis cases
  4. Determine the percentage of sepsis cases categorized in #3 who received acute care (Type of Care = “1”) and were deceased at discharge (Disposition of Patient = “20”)


Acute-care inpatient discharges meeting the SEP-3 proxy sepsis case definition during the measurement timeframe.


Acute-care inpatient discharges meeting the SEP-3 proxy sepsis case definition during the measurement timeframe with a discharge disposition of “Expired.”


CodeCode Description
A02.1Salmonella sepsis
A20.7Septicemic plague
A21.7Generalized tularemia
A22.7Anthrax sepsis
A26.7Erysipelothrix sepsis
A32.7Listerial sepsis
A39.1Waterhouse-Friderichsen syndrome
A39.2Acute meningococcemia
A39.3Chronic meningococcemia
A39.4Meningococcemia, unspecified
A40.xStreptococcal sepsis
A41.xOther sepsis
A42.7Actinomycotic sepsis
A54.86Gonococcal sepsis
B00.7Disseminated herpesviral disease
B37.7Candidal sepsis
I26.01Septic pulmonary embolism with acute cor pulmonale
I26.90Septic pulmonary embolism without acute cor pulmonale
I76Septic arterial embolism
O03.37Sepsis following incomplete spontaneous abortion
O03.87Sepsis following complete or unsp spontaneous abortion
O04.87Sepsis following (induced) termination of pregnancy
O07.37Sepsis following failed attempted termination of pregnancy
O08.82Sepsis following ectopic and molar pregnancy
O85Puerperal sepsis
O86.04Sepsis following an obstetrical procedure
O86.09Sepsis following an obstetrical procedure other surgical site
O86.81Puerperal septic thrombophlebitis
O88.3xObstetric pyemic and septic embolism
P36.xBacterial sepsis of newborn
R65.2xSevere Sepsis
T81.12xxPostprocedural septic shock
T81.44xxSepsis following a procedure


Code   Code Description
A39.1Waterhouse-Friderichsen syndrome
D65Disseminated intravascular coagulation [defibrination syndrome]
D69.59Other secondary thrombocytopenia
D69.6Thrombocytopenia, unspecified
D69.8Other specified hemorrhagic conditions
D69.9Hemorrhagic condition, unspecified
E872.0Acidosis, unspecified
E872.1Acute metabolic acidosis
E872.2Chronic metabolic acidosis
E872.9Other acidosis
E87.4Mixed disorder of acid-base balance
F05Delirium due to known physiological condition
F06.0Psychotic disorder with hallucinations due to known physiological condition
F06.1Catatonic disorder due to known physiological condition
F06.2Psychotic disorder with delusions due to known physiological condition
G62.81Critical illness polyneuropathy
G72.81Critical illness myopathy
G93.4xOther and unspecified encephalopathy
G93.6Cerebral edema
G93.82Brain death
G93.9Disorder of brain, unspecified
G96.81Intracranial hypotension
G96.810Intracranial hypotension, unspecified
G96.811Intracranial hypotension, spontaneous
G96.819Other intracranial hypotension
G96.89Other specified disorders of central nervous system
I46.8Cardiac arrest due to other underlying condition
I46.9Cardiac arrest, cause unspecified
I95.1Orthostatic hypotension
I95.89Other hypotension
I95.9Hypotension, unspecified
J80Acute respiratory distress syndrome
J96.0xAcute respiratory failure
J96.2xAcute and chronic respiratory failure
J96.9xRespiratory failure, unspecified
J98.01Acute bronchospasm
J98.9Respiratory disorder, unspecified
J99Respiratory disorders in diseases classified elsewhere
K59.81Ogilvie syndrome
K72.0xAcute and subacute hepatic failure
K72.9xHepatic failure, unspecified
K76.2Central hemorrhagic necrosis of liver
K76.3Infarction of liver
K76.7Hepatorenal syndrome
M35.81Multisystem inflammatory syndrome
N17.xAcute kidney failure
N19Unspecified kidney failure
R00.0Tachycardia, unspecified
R00.1Bradycardia, unspecified
R03.1Nonspecific low blood-pressure reading
R06.00Dyspnea unspecified
R06.03Acute respiratory distress
R06.09Other forms of dyspnea
R06.82Tachypnea, not elsewhere classified
R06.89Other abnormalities of breathing
R09.2Respiratory arrest
R40.20Unspecified coma
R40.211xComa scale, eyes open, never
R40.212xComa scale, eyes open, to pain
R40.213xComa scale, eyes open, to sound
R40.221xComa scale, best verbal response, none
R40.222xComa scale, best verbal response, incomprehensible words
R40.223xComa scale, best verbal response, inappropriate words
R40.224xComa scale, best verbal response, confused conversation
R40.231xComa scale, best motor response, none
R40.232xComa scale, best motor response, extension
R40.233xComa scale, best motor response, abnormal
R40.234xComa scale, best motor response, flexion withdrawal
R40.235xComa scale, best motor response, localizes pain
R40.242xGlasgow coma scale score 9-12
R40.243xGlasgow coma scale score 3-8
R40.244xOther coma, without documented Glasgow coma scale score, or with partial score reported
R40.3Persistent vegetative state
R57.xShock, not elsewhere classified
R65.2xSevere sepsis
T81.12xxPostprocedural septic shock